Peripheral Vascular Disease

Peripheral vascular disease is a common circulatory problem that involves the narrowing of vessels that carry blood away from the heart. Plaque, a substance made up of fat and cholesterol, builds up on the inside walls of the arteries and restricts normal blood flow.

This buildup of plaque is called atherosclerosis, or hardening of the arteries. Atherosclerosis can affect arteries anywhere in the body. When it affects the arteries of the heart, it is called coronary artery disease and can cause a heart attack. When it affects the arteries supplying the brain, it is called carotid artery disease and can lead to a stroke.

Atherosclerosis in the arteries that supply blood to the kidneys, stomach, arms, leg or feet is called peripheral ​vascular disease (PVD). 

Risk factors for developing the condition include smoking, diabetes, age, being overweight, and elevated blood pressure and cholesterol levels. Smoking is more likely than any of the other risk factors to cause P​VD. In fact, a smoker’s risk can be up to four times higher than a nonsmoker’s.

If you have P​VD, you are more likely to develop other forms of cardiovascular disease. Compared to the rest of the population, people with P​VD increase their risk of coronary artery disease, heart attack, stroke or mini stroke.

One of the first signs of P​VD can be painful cramping or fatigue in the legs and buttocks that occurs during activity, but stops during rest. However, approximately half of people with the disease have mild or no symptoms.

The condition can also cause leg numbness or weakness, cold legs or feet, skin color changes in the arms or legs, hair loss on feet and legs, toe or foot sores that heal slowly, and burning or achy feet and toes when resting or lying down. In advanced stages, blood flow to a leg or foot can be severely blocked, causing tissue death that may result in amputation.

Diagnosing P​VD can be done through an ankle-brachial index test, which compares blood pressure levels in the ankle and arm. Angiography, a form of imaging that uses a dye injected into the blood vessels, allows the doctor to watch blood flow through the arteries as it happens. A medical history, physical exam or ultrasound also may be used to diagnose P​VD.

People diagnosed with P​VD can usually be treated with lifestyle changes, medications or a combination of both. Lifestyle changes include smoking cessation, diabetes management, blood pressure control, exercise and a healthy diet.

Medications may be prescribed to lower cholesterol or blood pressure, control blood sugar (for diabetics), prevent blood clots or relieve certain symptoms. In some cases, however, surgery may be necessary to open vessels using a balloon catheter (a small, hollow tube).

Doctors may bypass the blocked vessel using either a graft or directly inject a clot-dissolving drug into the artery. In some cases, a stent (mesh tube) is inserted to keep the vessel open.

Leg pain, numbness or other symptoms should not be dismissed as normal aches and pains of aging. Early diagnosis and treatment of P​VD is important to not only protect your health, but also decrease your risk of heart attack or stroke.

To find out more about P​VD, talk to your doctor or call 1-866-358-4DOC (4362) to find a physician near you.